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肝腹水严重吗?怎么预防肝腹水?

发布时间:2016-06-20   问大夫  责任编辑:红豆

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我们身边多多少少会有肝腹水患者,但很多人还是对肝腹水不了解。不知道肝腹水的起因及临床表现有哪些?肝腹水到底是否严重呢?在日常生活中该如何去预防肝腹水呢?今天,就跟小编一起去看看了解下吧!

肝腹水
肝硬化腹水俗称肝腹水。正常人腹腔内有少量的游离腹水,一般为50毫升左右,起着维持脏器间润滑作用,当腹腔内出现过多游离液体时,称为腹水。肝硬化腹水是一种慢性肝病。由大块型、结节型、弥漫型的肝细胞性变,坏死、再生;再生、坏死,促使组织纤维增生和瘢痕的收缩,致使肝质变硬,形成肝硬化。肝硬化肝功能减退引起门静脉高压,导致脾肿大,对蛋白质和维生素的不吸收而渗漏出的蛋白液,形成了腹水症。
肝腹水的症状
肝腹水是肝硬化最突出的临床表现;失代偿期患者75%以上有腹水。腹水形成的机制为钠、水的过量潴留,与下列腹腔局部因素和全身因素有关:
1、门静脉压力增高:超过300mmH2O时,腹腔内脏血管床静水压增高,组织液回吸收减少而漏入腹腔。
2、低白蛋白血症:白蛋低于31g/L时,血浆胶体渗透压降低,致血液成分外渗。
3、淋巴液生成过多:肝静脉回流受阻时,血将自肝窦壁渗透至窦旁间隙,致胆淋巴液生成增多(每日约7-11L,正常为1-3L),超过胸导管引流的能力,淋巴液自肝包膜和肝门淋巴管渗出至腹腔。
4、继发性醛固酮增多致肾钠重吸收增加。
5、抗利尿激素分泌增多致水的重吸收增加。
6、有效循环血容量不足:致交感神经活动增加,前列腺素、心房以及激肽释放酶-激肽活性降低,从而导致肾血流量、排钠和排尿量减少。
上述多种因素,在腹水形成和持续阶段所起的作用有所侧重,其中肝功能不全和门静脉高压贯穿整个过程。腹水出现前常有腹胀,大量水使腹部膨隆、腹壁绷紧发高亮,状如蛙腹,患者行走困难,有时膈显著抬高,出现呼吸和脐疝。部分患者伴有胸水,多见于右侧,系腹水通过膈淋巴管或经瓣性开口进入胸腔所致。
肝腹水的起因
腹水最常见的病因是肝硬化,特别是酒精性肝硬化。其他肝原性病因包括慢性肝炎,尚无肝硬化的重型酒精性肝炎和肝静脉阻塞(Budd-Chiari综合征) 门静脉血栓形成时除非同时存在肝功能损害,否则也不会发生腹水,腹水的非肝源性病因有全身性疾病(如心衰、肾病综合症、严重低白蛋白血症及缩窄性心包炎)引起的全身体液潴留和腹腔内疾病(如癌变和结核性腹膜炎) 甲状性功能减退偶尔引起明显腹水、胰腺炎则罕见引起大量腹水(胰源性腹水) 肾衰病人,特别是进行血液透析的病人偶尔发生无法解释的腹水(肾源性腹水)。

1、门静脉高压:肝门静脉和下腔静脉又称门腔静脉,它是肝脏与其他部位血液循环的联结处。也是肝动脉和肝静脉出入的必经之路。在正常情况下其动静脉血管床的容量基本相等,输入血流和输出血流的量处于平衡状态。
肝硬化时,由于肝细胞变性、坏死、纤维组织增生,致肝内血管床受压、扭曲、变形、狭窄,阻塞了血管,使肝窦淤血,血流量大大降低,输入量明显大于输出量,使门腔静脉压力升高。同时,毛细血管静脉压力也升高,久而久之,胃肠道、肠系膜、腹膜等血液回流受阻,血管通透性升高,血液中的血浆成分外漏,形成了腹水。
2、低蛋白血症:是由于肝脏不能将胃肠消化吸收的营养物质合成白蛋白的缘故。由于血清白蛋白的降低,血管内胶体渗透压下降,血浆成分外渗而形成腹水。
3、内分泌失调:活动性肝硬化时,因肝脏对抗利尿激素的灭活作用大大减退,其含量升高,而使排尿减少,也可引起浮肿和腹水。
4、淋巴回流障碍:人体的淋巴循环又称第三循环,指位于动脉、静脉、毛细血管以外的一个循环系统。正常人无处没有淋巴循环,特别是肝窦和肝细胞之间,有着丰富的淋巴液。由于病变,肝脏不但使门腔静脉压力升高,也使淋巴自压力升高,管腔扩张,淋巴回流障碍,使淋巴液外溢,形成腹水。
肝腹水严重吗

肝腹水是肝硬化肝功能进入失代偿期最为显着的表现,腹水的出现表示肝硬化患者的病情开始恶化,由于肝腹水出现的初期没有什么特异性的症状,而且不影响正常生活,所以很多人不重视,没有意识到肝腹水的危害而延误治疗时间,导致病情恶化。

肝腹水不及时得的进行治疗,到了晚起,患者还会出现肝性脑病和上消化道出血,如果肝腹水患者不注意治疗和保养,很容易爆发并发症并死亡。健客网小编给大家详细的介绍一下肝腹水对肝脏有哪些危害,希望肝硬化患者不论有没有出现腹水,都要重视这个疾病,注意及时治疗和日常护理,防止疾病威胁生命。

肝腹水的治疗

【原发病的治疗】

腹水的治疗方案应依原发病而定。如结核性腹膜炎时应给予抗结核治疗;对腹腔脏器穿孔引起的化脓性腹膜炎应予外科治疗;对肿瘤性腹水则应根据病情给予手术切除、化疗、放疗或介入治疗。

【基础治疗

包括卧床休息和饮食治疗。腹水预示疾病的严重性。不论何种病因所致的腹水,都不能忽视基础治疗。

【卧床休息】

卧床休息对心、肝、肾功能的恢复都极为重要,有利于腹水的消退。卧床休息一方面可增加肝血流量,降低肝代谢负荷,促进腹水经隔膜的淋巴间隙重吸收;另一方面,能使肾血流量增加,改善肾灌注,消除水钠潴留。

【饮食治疗】

丰富的营养、足够的热卡对疾病的恢复是必要的。补给内容应因病而异,如低蛋白血症时应补充蛋白质及维生素;而对于严重肾功能和肝功能衰竭者,蛋白质则应有所限制,以碳水化合物为主;对于肝性腹水,应有足够热卡,每日保证热量在2000Kcal以上,以补充碳水化合物为主,蛋白质每天11.2g/kg,肝性脑病时蛋白应限制在每日0.5g/kg左右。

应补充适量脂肪。为了减少分解代谢,肝硬化病人应提倡两餐之间再进食。高歌等报道对28例顽固性肝硬化腹水患者,在原治疗基础上,短期静脉给予20%脂肪乳250ml,隔日一次,56次为一疗程。结果显示病人精神、食欲均显著改善,16例腹水消退,10例腹水减少,认为20% 脂肪乳剂配合治疗有助于改善肝硬化顽固性腹水。

【中医治疗】

肝腹水临床辨证施治可分七型,分述如下:

1、气滞湿阻:

症状:腹大胀满,按之不坚,腹部青筋暴露,两胁胀痛,食欲不振,食后作胀,肢体困倦,小便短少。舌苔白腻,脉弦滑。

治则:疏肝理气,健脾除湿。

方药:柴胡、枳壳、香附白芍、陈皮、川芎、厚朴、苍术、泽泻茯苓、大腹皮、肉桂

2、气滞血瘀:

症状:腹大坚满,青筋暴露,胁下肿块刺痛,面色黎黑,皮肤可见丝纹状血痣,手掌赤痕,口干渴,但欲漱口而不欲咽下,大便色黑,唇色紫暗,舌质紫暗或有瘀斑,舌下静脉曲张。脉细涩。

治则:活血化瘀,利水消胀。

方药:当归、赤芍、川芎、元胡、莪术、三棱、大黄、瞿麦、茯苓、大腹皮、桑皮、枳壳、红花

3、湿热蕴结:

症状:腹大坚满,脘腹撑急胀痛,烦热口苦,渴而不欲饮,小便赤涩,大便秘结,舌尖边红苔黄腻,脉弦数。

治则:清热利湿,攻下逐水。

方药:黄芩、黄连、厚朴、枳壳、陈皮、半夏、猪苓、茯苓、泽泻茵陈大黄、栀子。

4、寒湿困脾。

症状:腹大胀满,按之如囊裹水,胸脘胀闷,得热稍舒,精神困倦,怯寒懒动,小便少,大便溏,舌苔白腻脉缓。

治则:温中化湿。

方药:茯苓、白术、厚朴、大腹皮、木香、附子、干姜、青皮、枳壳。

5、脾肾阳虚

症状:腹部胀大,入暮益甚,控之不坚,兼有面色晦滞,畏寒肢冷,身体疲倦,尿少便溏或下肢浮肿,舌质淡胖苔薄白滑。脉沉细无力。

治则:温补脾肾,化气行水。

方药:熟地、山萸、山药、丹皮、泽泻、茯苓、附子、肉桂车前子、猪苓、黄芪

6、肝肾阴虚

症状:腹大胀满,甚则青筋暴露,形体消瘦,面色萎黄或面黑唇紫,口燥心烦,手足心热,尿少黄短,大便干,或见齿鼻衄血。舌质红降少津无苔脉弦细数。

治则:滋养肝肾,凉血化瘀。

方药:熟地沙参、枸杞子、麦冬、川楝子、当归、川芎、赤芍、元胡、桃仁红花、鳖甲。

7、气血两虚型:头晕心悸,面色无华,神疲乏力,食欲不振,两胁隐痛,舌质淡苔薄白,脉象虚弱。

治则:补益气血

方药:太子参黄芪何首乌、云苓、炒白术、当归、阿胶、丹参、郁金木香连翘、桑椹。

如何预防肝腹水

1、肝硬化患者必须戒烟戒酒:酒精经过代谢产生的甲醛对肝脏的危害是非常大的,肝硬化患者本身肝功能已被损害,此时若再饮酒,易加快病情发展的速度,还极易形成酒精肝。

2、肝硬化患者应选择低盐、适度蛋白质、低脂肪饮食:适当进食富含维生素食物、选择多纤维,少辛辣,无刺激性和较软的食物。

3、预防感染:肝硬化患者抵抗能力低下,极易发生腹膜和其他感染。所以,肝硬化病人应避免接触传染病者,一旦发生感染,应早期、彻底治。

4、避免使用损肝药物:常见易致肝损害药物有200多种,如四环素、氯霉素、红霉素等,应禁用或慎用。

5、防治并发症:肝腹水患者容易并发上消化道大出血、肝性脑病、肾脏疾病、溃疡病、血液病、腹泻、电解质紊乱等,要积极治疗,尽量减少对肝脏损害。

最后小编提醒大家:由于肝腹水对患者身心造成的危害很大,所以大家在平日的生活和学习中要对这一疾病进行相对应的预防,一旦发现自己患有肝腹水,要及早的去正规的医院进行有效的治疗。

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